Same supplement.
Different brand.
Big difference.
We grade every recommendation by the human trial data behind it, then say plainly who it's for and who should skip it.
- Reviewed
- Researched
- No hype
- Just facts
Same compound
Start with the problem
What are you actually trying to fix?
Pick one and we'll show only what has human trial evidence behind it. Often that's a shorter list than you were hoping for.
Falling asleep, staying asleep, waking up less
3 guides cover this.
- Moderate evidence
Magnesium glycinate
200-400mg elemental magnesium per day, in the evening
Read the evidence - Moderate evidence
Ashwagandha
300-600mg standardized root extract (like KSM-66 or Sensoril) per day
Read the evidence - Mixed evidence
CBD
Trial doses for anxiety range 300-600mg (acute, single dose); most consumer products deliver far less per serving
Read the evidence
The scale itself
Four rungs. Click one to see what earns it.
What earns a strong evidence
Multiple randomized controlled trials in humans, pointing the same way, from independent research groups.
Landed here
Interactive
Read a label the way we do
A typical fish oil panel, line by line. Tap any line to see whether it tells you something real or is there to make the bottle look stronger than it is.
Supplement facts, annotated
Figures are the industry-typical case described in our omega-3 guide, not a specific brand's product.
This number is not the dose
1000mg describes the weight of the oil in the softgel, not the amount of the two omega-3s that actually do anything. This is the single most common reason people take fish oil for months and feel nothing.
Read the omega-3 guideHow we work
Better questions, then healthier choices.
Graded, never ranked
Every guide carries a grade based on trial count, consistency, and effect size. Popularity does not move it. When the evidence is weak, the grade says weak.
Dosing that matches the trials
A "1000mg" fish oil softgel is often 300mg of what actually works. We print the difference.
Who should skip it
Interactions, conditions, and the cases where the research simply does not apply to you.
Everything at a glance
Every supplement we cover, sorted by evidence
Tap a column header to re-sort. Only one compound here earns a strong grade, which tells you most of what you need to know about this category.
 Creatine monohydratePerformance | Strong evidence | 3-5g per day, any time, taken consistently | Build muscleMore energy | Read |
|---|---|---|---|---|
 Semaglutide vs. tirzepatidePeptides & GLP-1s | Strong evidence | Semaglutide up to 2.4mg/week; tirzepatide up to 15mg/week, both titrated over months under a prescriber | More energy | Read |
 Vitamin D3Foundational | Moderate evidence | 1000-2000 IU/day for maintenance; higher short-term doses require a blood test and a plan | Immune supportMore energyHeart health | Read |
 Omega-3 (EPA/DHA)Foundational | Moderate evidence | 1-2g combined EPA+DHA per day; check the label, not just the softgel size | Heart healthBetter skin | Read |
 Magnesium glycinateFoundational | Moderate evidence | 200-400mg elemental magnesium per day, in the evening | Sleep betterLower stressBuild muscle | Read |
 AshwagandhaStress & sleep | Moderate evidence | 300-600mg standardized root extract (like KSM-66 or Sensoril) per day | Lower stressSleep better | Read |
 NAD+ and sermorelinPeptides & GLP-1s | Mixed evidence | NAD+ IV protocols vary widely by clinic (250-1000mg per session); sermorelin commonly 200-300mcg nightly, both prescribed and monitored | More energy | Read |
 CBDStress & sleep | Mixed evidence | Trial doses for anxiety range 300-600mg (acute, single dose); most consumer products deliver far less per serving | Lower stressSleep better | Read |
 BPC-157Peptides & GLP-1s | Weak evidence | No established human dose exists; forum protocols commonly cite 250-500mcg/day, unvalidated in trials | Build muscle | Read |
 Hydrogen waterHydration & recovery | Weak evidence | No established dose; trial protocols typically used 0.5-1.5L of hydrogen-saturated water per day | More energy | Read |
Head to head
Two brands, same stated purity, different paperwork
formerly Limitless Life Nootropics
Price transparency
The same compound, across three vendors
BPC-157, TB-500 and GHK-Cu each appear in all three catalogs. Where a vendor doesn't print the exact SKU price openly, we show their own stated range instead of leaving the cell blank.
| Compound | BioLongevity Labs$55 to $300 typical | Limitless BiotechNot published publicly | Amino Club$19.95 to $150 typical, before sitewide discount codes |
|---|---|---|---|
| BPC-157 | $99.97view | Not published publiclyvendor's stated range, exact SKU price gated | $39.99view |
| TB-500 | $164.97view | Not published publiclyvendor's stated range, exact SKU price gated | $39.99view |
| GHK-Cu | $84.97view | Not published publiclyvendor's stated range, exact SKU price gated | $29.99view |
Prices as listed on each vendor's own product page on the date shown in their review. Vendors change pricing without notice, so treat these as a snapshot rather than a live quote.
Brands we've reviewed
The products, and what we could actually verify
$99.97
$164.97
$299.99
$1,999.99
$39.99
$39.99
From $83.25/month
From $83.25/month (12-month plan)
$69.99
$39.99
$32.99
$105.95
From $149/month
From $179/month
From $159/month
From $239/month
From $149/month
From $169/month
From $169/month (12-month prepay)
From $179/month
$1,299/month
From $139/month
From $179/month
From $169/month
From $239/month
From $139/month
From $69/month
From $119/month
$99/month
$149/month
From $89/month
From $69/month
$99/month
$49 with code FALL
$59 with code FALL
$24.99
$89.99Ranked by documentation
Eight picks, scored on what we could verify
Public COAs, batch-level testing and open pricing. Not health claims, and not paid placements.
Top picks
The best-documented listings, pulled straight from our rankings
Scored on public Certificates of Analysis, batch-level testing, and whether the price is visible without an account. This list updates automatically whenever a brand review changes, it isn't a separate hand-picked list.
We may earn a commission if you buy through links on this page, at no extra cost to you. It never changes a grade or a ranking. How we grade.
Start with the ones people ask about most
All guidesLatest, in Foundational
Best Supplements for Immune Support, Ranked by Evidence
Immune supplements are marketed as a category, but the four most common ones have four very different levels of evidence behind them.
Read it
What people search for most
The specific questions readers arrive with, each pointing at the guide that answers it.
- Creatine dosage
- Does creatine cause bloating
- Vitamin D3 dosage
- Vitamin D deficiency levels
- How much omega-3 per day
- Magnesium glycinate vs citrate
- Best magnesium for sleep
- Ashwagandha benefits and dosage
- BPC-157 vs TB-500
- Best peptide company
- Third party tested peptides
- BioLongevity Labs review
- Limitless Life Nootropics review
- Best documented research peptides
Already taking something? Find out where it stands.
Every guide names the trial dose, the side effects worth knowing, and exactly who the research says should be careful.
hype.See all guides